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第 21 卷  第 1 期  （总 108 期） 2004年1月

目    录

                             

药    剂

 葛根7,4′-二氧代醋酸黄豆苷元在大鼠体内的药物动力学研究 王淑君，张  品，孙  辉，等 (1)
盐酸环丙沙星缓释胶囊家犬体内生物利用度研究 邵瑞莹，唐  星，贺  亮 (4)
辣椒素脂质体在体外瘢痕组织中透皮吸收的研究 白  铭，张恒术，王  昆，等 (8)
复方愈麻美芬缓释片及其释放机理的研究 刘  欢，毕殿洲，王春龙 (11)
酸的HPLC测定及其药代动力学研究 张黎明，宋洪杰，侯晓红 (15)
维甲酸羟丙勃-β-环糊精包合物制备条件的优化及包合过程热力学参数的测定 姜典卓，王志宣，武凤兰 (18)

药物化学

6-（4-氨基苯基）-5-甲基-4，5-二氢-3（2H）-哒嗪酮的拆分及左西孟旦的合成

 张丽娟，宋宏锐，王玉玲，等 (22)

药物分析

 3-正丁基苯酞含量及有关物质测定的方法学研究 赵春顺，崔升淼，刘晓红，等 (24)
不同来源黄芩药材HPLC指纹图谱比较 肖丽和，王红艳，李发美，等 (28)
毛细管电泳法测定红毛五加茎皮中鸟苷的含量 王祝伟，孙毓庆  (32)
HPLC法测定蒙药那如-3丸中胡椒碱的含量 陶淑娟，王桂燕，毕开顺 (35)
HPLC法测定复方大青叶注射液中大黄素和大黄素甲醚的含量 李  磊，袁  波，李发美 (38)

药    理

 中国林蛙卵油的抗焦虑作用 佟  岩，徐  峰，陈  侠，等 (41)
　 SB224289对5-HT诱导的肺动脉平滑肌细胞增殖的影响 高山红，王怀良，刘卫民，等 (45)
　 甘油一酯转酰基酶药物治疗肥胖的新靶点 栾  洋，王  蕊，河野一弥，等 (48)
　 黄连解毒胶囊对大鼠血液流变学的影响 付晓春，王敏伟，卢方正，等 (52)
　 小儿清热止咳口腔速溶片药效学研究 高  鹏，王永圣，崔福德，等 (56)
　

大鼠急性心肌缺血-再灌注损伤时心肌超微结构的变化与白花前胡及前胡甲素的保护作用

 姜明燕，徐亚杰，杜  震，等 (59)
　 布洛芬川芎嗪酯的抗炎镇痛作用 马  涛，曹颖林，郑雪娜，等 (62)

生物药学

L-异亮氨酸发酵条件的研究

 王  菲，陈  宁，宋文军，等 (65)

综    述

药物基因组学与合理用药研究进展

 郦佳鸣，郦章安 (70)
微生物硫酸软骨素裂解酶的研究进展 蔡苏兰，阎浩林，何汉洲 (76)

Journal of Shenyang Pharmaceutical University

Vol.21    No.1    (Sum 108)    Jan. 2004

CONTENTS

Pharmacokinetic study on 7,4′-oxo-acetic acid daidzein in rats

                                                                  ...WANG Shu-jun, ZHANG Pin, SUN Hui, et al. (1)

Bioavailability  study of ciprofloxacin hydrochloride sustained-release capsules in dogs

                                                                       ...SHAO Rui-ying, TANG Xing, HE Liang  (4)

In vitro study on diffusion of liposomal capsaicin through the human scar skin 

                                                                ...BAI Ming, ZHANG Heng-shu, WANG Kun, et al. (8)

Preparation of the compound sustained-release tablets of Yumameifen  and study on the release mechanism of three drugs from the sustained-release tablets

                                                                  ...LIU Huan, BI Dian-zhou, WANG Chun-long  (11)

Determination of mycophenolic acid, the active metabolite of mycophenolate mofetil in  rabbit plasma by HPLC and  harmacokinetic study                       ...ZHANG Li-ming, SONG Hong-jie, HOU Xiao-hong  (15)

Optimization of the conditions of making the inclusion of tretinoin by hydroxyl propyl beta cyclodextrin and assay of the   hermodynamical parameter of the including procedure

                                                             ...JIANG Dian-zhuo, WANG Zhi-xuan, WU Feng-lan  (18) 

Resolution of 6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one and synthesis of levosimendan                                         ...ZHANG Li-juan, SONG Hong-rui, WANG Yu-ling, et al. (22)

Determination of the content and the related substances of 3-n-butylphthalide in liposomes by RP-HPLC                                               ...ZHAO Chun-shun, CUI Sheng-miao, LIU Xiao-hong, et al. (24)

Comparative study on HPLC-FPS of Radix Scutellariae of various sources 

                                                             ...XIAO Li-he, WANG Hong-yan, LI Fa-mei, et al. (28) 

Determination of the content of guanosine in the extract of Acanthopanax giraldii Harms by capillary zone electrophoresis                                                        ...WANG Zhu-wei, SUN Yu-qing  (32)

Determination of the content of piperine in the Mongolian recipe Naru  by HPLC

                                                                ...TAO Shu-juan, WANG Gui-yuan, BI Kai-shun  (35) 

Determination of the contents of rhein and physcione in the Injectio Folii Isatidis Composita by HPLC                                                                ...LI Lei, YUAN Bo, LI Fa-mei  (38)

Anti-anxiety effects of the egg oil of Rana temporaria chensinensis David 

                                                                      ...TONG Yan, XU Feng, CHEN Xia, et al. (41)

Effects of  SB224289 on the pulmonary vascular smooth muscle cell proliferation induced by 5-HT 

                                                      ...GAO Shan-hong, WANG Huai-liang, LIU Wei-min, et al. (45) 

Role of monoacylglycerol acyltransferase in obesity    ...LUAN Yang, WANG Rui, Kazuya Kawano, et al. (48) 

Effect of Huanglian Jiedu Capsules on hemorheology of normal rats 

                                                        ...FU Xiao-chun, WANG Min-wei, LU Fang-zheng, et al. (52) 

Studies on the pharmacodynamics of Xiao'er Qingre Zhike Orally Disintegrating Tablets 

                                                             ...GAO Peng, WANG Yong-sheng, CUI Fu-de, et al. (56)

Change of myocardial ultrastructure and the protective effect of Peucedanum praeruptorum  Dunn and ...its effective   component (praeruptorin A,Pd-Ia) against acute myocardial ischemia-reperfusion injury in rats                                         ...JIANG Ming-yan, XU Ya-jie, DU Zhen, et al. (59) 

Anti-inflammatory and analgesic effects of ibuprofen tetramethylpyrazine ester 

                                                               ...MA Tao, CAO Ying-lin, ZHENG Xue-na, et al. (62)   

Studies on the fermentation conditions of L-iso-leucine 

                                                                ...WANG Fei, CHEN Ning, SONG Wen-jun, et al. (65) 

Advances of the study on pharmacogenomics and reasonable use of drugs

                                                                                ...LI Jia-ming, LI Zhang-an  (70)

Advances of the study on chondroitinases produced by microorganisms 

                                                                    ...CAI Su-lan, YAN Hao-lin, HE Han-zhou  (76)

　

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