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第 22 卷  第 6 期  （总 119 期） 2005年11月

目    次

                             

药    剂

硫酸沙丁胺醇油包水型口服纳米乳的制备及小肠吸收考察

 …毛世瑞，张  磊，李  茗，等 (401)
布比卡因缓释微球的制备及体外释药特性评价

…刘晓睿，丁平田，张  锦，等

 (405)
银杏叶提取物掩味方法筛选及口腔崩解片制备 …冯丽莉，胡  杰，黄  华，等 (409)
重组水蛭素肠溶包衣微丸的制备及体外释放行为考察 …王  征，杨  丽，唐  星，等 (413)

药物化学

索法酮的合成

 …王绍杰，郑洪伟，赵存良，等 (417)
　 吉莫斯特的合成 …郝玲花，周  洁，孙延龙，等 (420)
　 广金钱草的化学成分 …刘  茁，董  焱，王  宁，等 (422)

药物分析

注射用氟罗沙星的质量控制标准及安全性

 …孙  进，何仲贵 (425)
CD-01盐酸盐中有关物质的HPLC法检测及稳定性考察 …李  宁，刘  宇，宫  平，等 (429)
RP-HPLC法测定壳聚糖微球中5-氟尿嘧啶的包封率 …李可欣，陈大为，赵秀丽，等 (434)
RP-HPLC法测定复方托吡卡胺滴眼液中盐酸去氧肾上腺素与托吡卡胺两组分含量 …郭晓明，宫晓光，范洪涛，等 (438)

药    理

注射用苦碟子的抗凝与纤溶活性

 …王彩霞，何晓静，刘玉兰 (441)
　 新疆雪莲组织培养物的抗辐射作用(英文) …贾景明，吴春福，于  海，等 (444)
　 接骨木中的三萜类化合物及其对类成骨细胞UMR106的作用 …杨序娟，王乃利，黄文秀，等 (449)
　 胆甾-4-烯-3β，6β-二醇双琥珀酸单酯双乙醇胺盐的体内抗癌活性及对血象的影响 …刘跃金，吴春福，容世宏 (453)
　 大蒜油亚微乳的安全性及体外抗真菌作用 …郭  涛，储晓琴，颜  鸣，等 (458)

综    述

阿维菌素产生菌的生物技术改造研究进展

 …刘婷婷，蔡苏兰，阎浩林 (463)
　

Caco-2细胞模型在口服药物吸收研究中的应用

 …高  坤，孙  进，何仲贵 (469)
　 超临界流体技术原理及在药学中的应用与展望 …王齐放，李三鸣，赵  哲 (475)

Journal of Shenyang Pharmaceutical University

Vol.22    No.6    (Sum 119)    Nov. 2005

CONTENTS

Formulation and characterization of water-in-oil nanoemulsion of salbutamol sulfate for peroral administration

                                                                                                                                                                                …MAO Shi-rui, ZHANG Lei, LI Ming, et al. (401)

Preparation of sustained-release poly(D,L-lactide-co-glycolide) microspheres containing bupivacaine and the evaluation of drug release in vitro

                                                                                                                                                                …LIU Xiao-rui，DING Ping-tian，ZHANG Jin, et al. (405)

Study on masking methods to dispel the bitterness of Extractum Ginkgo Siccum(EGS) and its preparation of orally disintegrating tablets

                                                                                                                                                                                      …FENG Li-li,HU Jie, HUANG Hua, et al. (409)

Preparation of recombinant hirudin enteric coated-pellets and exploration on its released behaviour in vitro

                                                                                                                                                                    …WANG Zheng，YANG Li，TANG Xing，et al. (413)

Synthesis of sofalcone

                                                                                                                                        …WANG Shao-jie，ZHENG Hong-wei，ZHAO Cun-liang，et al. (417)

Studies on the synthesis of gimeracil

                                                                                                                                                                     …HAO Ling-hua, ZHOU Jie, SUN Yan-long, et al. (420)

Chemical studies on the constituents of Desmodium styracifolium (Osb.)Merr.

                                                                                                                                                                              …LIU Zhuo, DONG Yan, WANG Ning, et al. (422)

Quality control and safety evaluation of fleroxacin for injection

                                                                                                                                                                                                               …SUN Jin, HE Zhong-gui (425)

HPLC determination of the related substances of CD-01 hydrochloride and its stability

                                                                                                                                                                                            …LI Ning, LIU Yu, GONG Ping, et al. (429)

Establishment of drug content determination method in chitosan microspheres

                                                                                                                                                                            …LI Ke-xin, CHEN Da-wei, ZHAO Xiu-li, et al. (434)

Determination of the contents of phenylephrine hydrochloride and tropicamide in compound tropicamide eye drops by RP-HPLC

                                                                                                                                              …GUO Xiao-ming，GONG Xiao-guang，FAN Hong-tao, et al. (438)

Anticoagulation and fibrinolysis activities of the injection of Ixeris sonchifolia(Bge.) Hance

                                                                                                                                                                               …WANG Cai-xia, HE Xiao-jing，LIU Yu-lan (441)

Anti-radiation activity of the tissue culture of Saussurea involucrate Kar.et Kir.

                                                                                                                                                                         …JIA Jing-ming, WU Chun-fu, YU Hai,et al. (444)

Studies of triterpenoids isolated from Sambucus williamsii Hance and their effects on UMR106 cell proliferation and alkaline phosphatase activity

                                                                                                                                                         …YANG Xu-juan, WANG Nai-li, WONG Man-sau, et al. (449)

In vivo anticancer activity of bisethanolamine salt of cholest-4-en-3β，6β-diol bishemisuccinate and its effects on hemogram

                                                                                                                                                                        …LIU Yue-jin，WU Chun-fu，RONG Shi-hong (453)

Study on the safety of garlic oil submicron emulsion and antifugal effects in vitro

                                                                                                                                                                             …GUO Tao, CHU Xiao-qin, YAN Ming, et al. (458)

Research progresses on engineering Streptomyces avermectinius through biotechnology

                                                                                                                                                                                  …LIU Ting-ting, CAI Su-lan, YAN Hao-lin (463)

Important application of Caco-2 cell monolayers in the study of the intestinal oral absorption

                                                                                                                                                                                            …GAO Kun, SUN Jin, HE Zhong-gui (469)

Principle of supercritical fluid technology and its application in pharmaceutics

                                                                                                                                                                                …WANG Qi-fang, LI San-ming, ZHAO Zhe (475)

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