2007-01-24

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第 24 卷第 1 期（总 132 期） 2007年1月

目次

药剂	提高难溶性药物尼群地平溶出率和口服生物利用度的研究	…张玉龙，林文辉，王亮，等	(1)
	胰岛素肠溶PLGA纳米粒的制备及体内外性质的评价	…陶安进，张立强，石凯，等	(9)
	齐多夫定棕榈酸酯及其脂质体在小鼠和大鼠血浆中的稳定性	…雷杰杰，田文艳，孙红卫，等	(13)
	均匀设计法制备苦参碱渗透泵型控释片	…张丹，孙英华，刘艳，等	(16)
药物化学	蒙古黄芪化学成分的分离与鉴定	…李瑞芬，周玉枝，乔莉，等	(20)
	蓝刺头茎叶中化学成分的分离与鉴定	…张玉伟，李铣，孟大利，等	(23)
药物分析	HPLC法测定小承气汤中大黄酸和厚朴酚的含量	…胡晓静，高轶哲，李飞，等	(26)
	HPLC法测定中药白英中薯蓣皂苷元的含量	…孙立新，孟楠，何珉，等	(29)
	大鼠肝微粒体中葛根素的液相色谱-质谱测定法及药物代谢动力学	…崔升淼，赵春顺，高坤，等	(32)
	HPLC-ELSD法测定注射用洋参生脉粉针剂中皂苷类成分的含量	…尹恬，刘彦生，于叶玲，等	(37)
药理	新化合物O325H的抗糖尿病作用	…徐成，王莉莉，龙隆，等	(40)
	吴茱萸碱在诱导人黑色素瘤A375-S2细胞凋亡过程中对SIRT1和p53蛋白的影响	…王澈，李菘，王敏伟	(45)
	酮色林和坎地沙坦对清醒自由活动自发高血压大鼠压力反射功能的影响	…付彦君，王敏伟	(49)
	5, 8-二取代喹唑啉类化合物LJK-11对HER2高表达肿瘤细胞的作用和分子机制初探	…秦莉莉，金毅，龙亚秋，等	(53)
药学信息	Internet网上免费检索国外药学专利的方法	…常悦，王桂清	(57)
综述	胰岛细胞系模型的研究进展	…刘铮，只德贤，王敏伟	(61)

Journal of Shenyang Pharmaceutical University

Vol.24 No.1 (Sum 132) Jan. 2007

CONTENTS

Improvement of dissolution rate and oral bioavailability of poorly water soluble drug nitrendipine

…ZHANG Yu-long, LIN Wen-hui, WANG Liang, et al. (1)

Preparation and characterization of insulin loaded PLGA-HP55 nanoparticles

…TAO An-jin, ZHANG Li-qiang, SHI Kai, et al. (9)

Stabilities of azidothymidine palmitate and its liposome preparations in mice and rats blood plasma

…LEI Jie-jie, TIAN Wen-yan, SUN Hong-wei, et al.(13)

Preparation of controlled release tablets of matrine with uniform design

…ZHANG Dan, SUN Ying-hua, LIU Yan, et al. (16)

Chemical constituents of Astragalus membranaceus Bge.var. mongholicus (Bge.) Hsiao

…LI Rui-fen, ZHOU Yu-zhi, QIAO Li, et al. (20)

Chemical constituents from the stem and leaves of Echinops latifolius Tausch.

…ZHANG Yu-wei, LI Xian, MENG Da-li, et al. (23)

Determination of the contents of rhein and magnolol in the Xiaochengqi decoction by HPLC

…HU Xiao-jing, GAO Yi-zhe, LI fei, et al. (26)

Determination of the contents of diosigenin of the Solanum lyratum Thvnb.by HPLC

…SUN Li-xin, MENG Nan, HE Min, et al. (29)

Determination of puerarin in rat liver microsomes by LC-MS and its pharmacokinetics

…CUI Sheng-miao, ZHAO Chun-shun, GAO Kun, et al. (32)

Quantitative determination of saponins of Panax quinquefolium L.in Yangshen shengmai freezing-dry preparation for injection by HPLC-ELSD

…YIN Tian, LIU Yan-sheng, YU Ye-ling, et al. (37)

Effects of the novel compound O325H on glucose and lipid metabolism

…XU Cheng, WANG Li-li, LONG Long, et al. (40)

Influences on SIRT1 and p53 in evodiamine-induced apoptosis in human melanoma A375-S2 cells

…WANG Che, LI Song，WANG Min-wei (45)

Effect of ketanserin and candesartan on arterial baroreflex in conscious spontaneous hypertensive rats

…FU Yan-jun, WANG Min-wei (49)

Effects and molecular mechanism of 5,8-disubstituted quinazolines-LJK-11 in HER2 overexpressing cells

…QIN Li-li, JIN Yi, LONG Ya-qiu,et al.(53)

Free method of searching foreign pharmaceutical patent in internet

…CHANG Yue，WANG Gui-qing(57)

Recent progress of cell line models derived from pancreatic islets

…LIU Zheng, ZHI De-xian, WANG Min-wei (61)

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